This quiz works best with JavaScript enabled. Home > Cbse > Class 12 > Science > Biology > Class 12 Biology Chapter 6 Molecular Basis Of Inheritance – Quiz 16 🏠 Homepage 📘 Download PDF Books 📕 Premium PDF Books Class 12 Biology Chapter 6 Molecular Basis Of Inheritance Quiz 16 (60 MCQs) Quiz Instructions Select an option to see the correct answer instantly. 1. Which of the following facts did Hershey and Chase make use of in trying to determine whether DNA or protein is the genetic material? A) DNA contains sulfur, whereas protein does not. B) DNA contains purines, whereas protein includes pyrimidines. C) DNA contains phosphorus, whereas protein does not. D) DNA contains nitrogen, whereas protein does not. Show Answer Correct Answer: C) DNA contains phosphorus, whereas protein does not. 2. Which of the following has dual functions? A) AUG. B) ACU. C) AUC. D) AUU. Show Answer Correct Answer: A) AUG. 3. Which is also called the sense strand? A) Template strand. B) Coding strand. C) 3'-5'. D) None of the above. Show Answer Correct Answer: A) Template strand. 4. The enzyme that unwinds the DNA to prepare for replication A) Polymerase. B) SynthaseTagsDNA replication enzymes. C) Replicase. D) Helicase. Show Answer Correct Answer: D) Helicase. 5. If a double-stranded DNA molecule contains 30% T, how much G does it contain? A) 20%. B) 40%. C) 30%. D) 50%. Show Answer Correct Answer: A) 20%. 6. Frederick Griffith's transforming principle demonstrated that: A) Proteins are the genetic material. B) A heat-stable agent from virulent bacteria can genetically alter nonvirulent bacteria. C) RNA is the hereditary molecule. D) Mutations cannot be inherited. Show Answer Correct Answer: B) A heat-stable agent from virulent bacteria can genetically alter nonvirulent bacteria. 7. The structure in chromatin seen as 'beads-on-string' when viewed under an electron microscope is called: A) Nucleosomes. B) Histone octamer. C) Nucleotides. D) Nucleosides. Show Answer Correct Answer: A) Nucleosomes. 8. Ligase is an enzyme required for A) Proofreading. B) Joining DNA bits. C) Renaturation of DNA. D) Breaking of DNA. Show Answer Correct Answer: B) Joining DNA bits. 9. DNA is a polymer made of ..... A) Fats. B) Sugars. C) Amino acids. D) Nucleotides. Show Answer Correct Answer: D) Nucleotides. 10. Harshey and Chase provided the final proof that DNA is the genetic material A) True. B) Flase. C) All the above. D) None of the above. Show Answer Correct Answer: A) True. 11. Nucleosome contains A) Only histone protein. B) Both DNA and histone protein. C) Only DNA. D) Both DNA and RNA. Show Answer Correct Answer: B) Both DNA and histone protein. 12. The technique developed by Frederick Sanger was crucial for: A) Protein synthesis. B) DNA sequencing. C) DNA fingerprinting. D) Gene cloning. Show Answer Correct Answer: B) DNA sequencing. 13. If a double stranded DNA has 20% of cytosine, Calcualte the percentage of adenine in DNA. A) 30 percentage. B) 40percentage. C) 50 percentage. D) 60 percentage. Show Answer Correct Answer: A) 30 percentage. 14. In the Meselson/Stahl experiment, which of the following results was observed in the CsCl2 density sedimentation separation of the DNA replication products after ONE generation in $^{14}$NH4Cl A) A single band of intermediate density. B) Two bands, one of high density and one of low density. C) Two bands, one of high density and one of intermediate density. D) Two bands, one of low density and one of intermediate density. Show Answer Correct Answer: D) Two bands, one of low density and one of intermediate density. 15. Name the person who discovered 'nuclein' A) Basel. B) Fredrick Miecher. C) Watson. D) Crick. Show Answer Correct Answer: B) Fredrick Miecher. 16. In the lac operon, the repressor protein is coded by: A) A gene. B) I gene. C) Y gene. D) Z gene. Show Answer Correct Answer: B) I gene. 17. A complex of ribosomes attached to a single strand of RNA is known as A) Polymer. B) Okazaki fragment. C) Polysome. D) Polypeptide. Show Answer Correct Answer: C) Polysome. 18. Telomere shortening puts a limit on the number of times a cell can divide. Research has shown that telomerase can extend the life span of cultured human cells. How might adding telomerase affect cellular aging? A) Telomerase shortens telomeres, which delays cellular aging. B) Telomerase would have no effect on cellular aging. C) Telomerase eliminates telomere shortening and slows aging. D) Telomerase will speed up the rate of cell proliferation. Show Answer Correct Answer: C) Telomerase eliminates telomere shortening and slows aging. 19. It is nonsense to think that DNA has- A) 2 types of nitrogenous base. B) 3 types of nitrogenous base. C) 6 types of nitrogenous base. D) 4 types of nitrogenous base. Show Answer Correct Answer: B) 3 types of nitrogenous base. 20. Chargraff's Rule says that A) Adenine will be equal to Cytosine. B) Cytosine will be equal to Thymine. C) Uracil will be equal to Guanine. D) Adenine will be equal to Thymine. Show Answer Correct Answer: D) Adenine will be equal to Thymine. 21. Which one of the following is not found in DNA? A) Nitrogen or Hydrogen. B) Carbon. C) Sulfur. D) Oxygen. Show Answer Correct Answer: C) Sulfur. 22. Who gave the X ray data for double helical model of DNA A) Francis Crick. B) Rosalind Franklin. C) Maurice Wilkins. D) James Watson. Show Answer Correct Answer: B) Rosalind Franklin. 23. In DNA replication, the primer is:- A) A small deoxyribonucleotide polymer. B) A small ribonucleotide polymer. C) Helix destabilizing protein. D) Enzyme taking part in joining nucleotides ofnew strand. Show Answer Correct Answer: B) A small ribonucleotide polymer. 24. Which of the following is a nonsense codon? A) AUG. B) GUG. C) CUG. D) UAG. Show Answer Correct Answer: D) UAG. 25. DNA has a alternate grooves- A) One major and one minor. B) Two major and one minor. C) One major and two minor. D) Two major and two minor. Show Answer Correct Answer: C) One major and two minor. 26. It became apparent to Watson and Crick after completion of their model that the DNA molecule could carry a vast amount of hereditary information. Which of the following characteristics of DNA is responsible for this? A) Complementary pairing of bases. B) Side groups of nitrogenous bases. C) Phosphate-sugar backbones. D) Sequence of bases. Show Answer Correct Answer: D) Sequence of bases. 27. In a mutation event, when adenine is replaced by guanine, it is a case of A) Transcription. B) Transition. C) Frame shift mutation. D) Transversion. Show Answer Correct Answer: B) Transition. 28. Select the incorreclty matched pair. A) Initation codons-AUG, GUG. B) Anticodons-mRNA. C) Methionine-AUG. D) Stop codons-UAA, UAG, UGA. Show Answer Correct Answer: B) Anticodons-mRNA. 29. A small circular piece of DNA found in bacteria are called ..... A) Plasmids. B) Prokaryotes. C) Vectors. D) Recombinants. Show Answer Correct Answer: A) Plasmids. 30. Which strand is synthesized continuously during DNA Replication A) Leading Strand. B) Lagging Strand. C) All the above. D) None of the above. Show Answer Correct Answer: A) Leading Strand. 31. The lac operon genes only become expressed if: A) Lactose binds to the repressor. B) Glucose binds to the repressor. C) Lactose binds to the operator. D) The repressor binds to the operator. Show Answer Correct Answer: A) Lactose binds to the repressor. 32. Which of the following is not involved in the initiation of replication? A) Ligase. B) DNA gyrase. C) Single-stranded binding protein. D) PrimaseTagsDNA replication enzymes. Show Answer Correct Answer: A) Ligase. 33. In Prokaryotes, gene reguoccurs at the level of A) Transcription. B) Post-translation. C) Post-transcription. D) Translation. Show Answer Correct Answer: A) Transcription. 34. Chemically, RNA is (i) reactive and (ii) stable as compared to DNA. A) (i) equally, (ii) equally. B) (i) less, (ii) more. C) (i) more, (ii) less. D) (i) more, (ii) equally. Show Answer Correct Answer: C) (i) more, (ii) less. 35. Assertion:Enzymes required for DNA replication are efficient enzymes Reason:They can polymerise large number of nucleotides in very short time A) Both assertion and reason are true and the reason is the correct explanation of assertion. B) Both assertion and reason are true but the reason is not the correct explanation of assertion. C) Assertion is true but reason is false. D) Both assertion and reason are false. Show Answer Correct Answer: A) Both assertion and reason are true and the reason is the correct explanation of assertion. 36. 5'-3' end of DNA strand is called A) Sense strand. B) Coding strand. C) Non-template strand. D) All of the above. Show Answer Correct Answer: D) All of the above. 37. The significant aspect of reverse transcription is A) The flow information from DNA to RNA. B) The flow information from RNA to DNA. C) The flow information from RNA to proteins. D) Both a and c. Show Answer Correct Answer: B) The flow information from RNA to DNA. 38. They year 2003 was celebrated as the 50th anniversary of discovery of A) Transposons by Barbare Me Clintock. B) Structure of DNA by Watson and Crick. C) Mendel's laws of inheritance. D) Biotechnology by Kary Muliis. Show Answer Correct Answer: B) Structure of DNA by Watson and Crick. 39. Lac operon is switched on in the presence of A) Fructose. B) Galactose. C) Glucose. D) Lactose. Show Answer Correct Answer: D) Lactose. 40. A base sequence is shown:ACAGTGC How would the base sequence be coded on mRNA? A) GUGACAU. B) CACUGUA. C) TGTCACG. D) UGUCACG. Show Answer Correct Answer: D) UGUCACG. 41. Which is the Codon containing A) Hn rna. B) M rna. C) R rna. D) T rna. Show Answer Correct Answer: B) M rna. 42. DNA finger printing is a technique in molecular biology. Arrange the following steps in sequence. 1) Blotting of DNA fragment to nitro cellulose. 2) Digestion of DNA by restriction endonuclease. 3) Detection of DNA by autoradiography. 4)Isolation of DNA, 5) separation of DNA fragments by electrophoresis A) 4 2 1 5 3. B) 4 3 5 1 2. C) 2 4 1 5 2. D) 4 2 5 1 3. Show Answer Correct Answer: D) 4 2 5 1 3. 43. Each set of three nitrogen bases that represents an amino acid is ..... A) An enzyme. B) A helix. C) A code. D) A codon. Show Answer Correct Answer: D) A codon. 44. DNA replication takes place at ..... phase of the cell cycle. A) S. B) M. C) G1. D) G2. Show Answer Correct Answer: A) S. 45. Both deoxyribose and ribose belong to a class of sugars called: A) Hexoses. B) Trioses. C) Polysaccharides. D) Pentoses. Show Answer Correct Answer: D) Pentoses. 46. The DNA strand that codes for protein is known as the ..... A) Intervening sequences. B) Introns. C) Control regions. D) Exons. Show Answer Correct Answer: D) Exons. 47. In transcription in eukaryotes, heterogenous nuclear RNA (hnRNA) is tmascribed by A) RNA polymerase I. B) RNA polymerase II. C) RNA polymerase III. D) All of these. Show Answer Correct Answer: B) RNA polymerase II. 48. One gene-one enzyme hypothesis was proposed by A) Watson. B) Beadle and Tatum. C) Chargaff. D) Meselson. Show Answer Correct Answer: B) Beadle and Tatum. 49. Which is the first step? A) DNA Helicase unwinds original DNA strand. B) RNA Primase lays down RNA primer for new nucleotide bases. C) DNA polymerase builds new strands by bring in new nucleotide bases. D) Ligase knits together fragments on lagging strandTagsDNA replication process. Show Answer Correct Answer: A) DNA Helicase unwinds original DNA strand. 50. Pick the correct pair with respect to primers used in DNA replication. A) RNA primer-for both prokaryotes and eukaryotes. B) DNA primer-for both prokaryotes and eukaryotes. C) DNA primer-for eukaryotes only. D) RNA primer-for prokaryotes only. Show Answer Correct Answer: A) RNA primer-for both prokaryotes and eukaryotes. 51. Which RNA carries amino acids? A) SnRNA. B) TRNA. C) HnRNA. D) MRNA. Show Answer Correct Answer: B) TRNA. 52. Which is the fourth step? A) DNA Helicase unwinds original DNA strand. B) RNA Primase lays down RNA primer for new nucleotide bases. C) DNA polymerase builds new strands by bring in new nucleotide bases. D) Ligase knits together fragments on lagging strandTagsDNA replication process. Show Answer Correct Answer: D) Ligase knits together fragments on lagging strandTagsDNA replication process. 53. Which enzyme proofreads the DNA after replication to catch any mistakes? A) Proof-read-ase. B) Primase. C) Helicase. D) DNA polymerase. Show Answer Correct Answer: D) DNA polymerase. 54. In the template with polarity 3'-5' the replication is A) Sometimes discontinuous. B) Continuous. C) Sometimes continuous. D) Discontinuous. Show Answer Correct Answer: B) Continuous. 55. This enzyme helps helicase unzip DNA by relieving supercoiling A) Topoisomerase. B) Exonuclease. C) DNA PolymeraseTagsDNA replication enzymes. D) DNA Primase. Show Answer Correct Answer: A) Topoisomerase. 56. Some viruses with RNA as genetic material has been reported A) True. B) False. C) All the above. D) None of the above. Show Answer Correct Answer: A) True. 57. The pitch of the DNA helix (one complete turn) is A) 3.4 nm. B) 2 nm. C) 10 nm. D) 34 nm. Show Answer Correct Answer: A) 3.4 nm. 58. Escherichia coli with completely radioactive DNA was allowed to replicate in nonradioactive medium for two generations. Percentage of bacteria with radioactive DNA is A) 50%. B) 12.5%. C) 25%. D) 100%. Show Answer Correct Answer: A) 50%. 59. Coding sequence or expressed sequence is A) Regulator. B) Exon. C) Intron. D) Structural gene. Show Answer Correct Answer: B) Exon. 60. In DNA replication, the resulting daughter molecules contain one strand of the original parental DNA and one new strand. What is the explanation for this phenomenon? A) DNA replication is not conservative. B) DNA replication is semiconservative. C) RNA synthesis is conservative. D) DNA replication is conservative. Show Answer Correct Answer: B) DNA replication is semiconservative. ← PreviousNext →Related QuizzesScience QuizzesClass 12 QuizzesClass 12 Biology Chapter 6 Molecular Basis Of Inheritance Quiz 1Class 12 Biology Chapter 6 Molecular Basis Of Inheritance Quiz 2Class 12 Biology Chapter 6 Molecular Basis Of Inheritance Quiz 3Class 12 Biology Chapter 6 Molecular Basis Of Inheritance Quiz 4Class 12 Biology Chapter 6 Molecular Basis Of Inheritance Quiz 5Class 12 Biology Chapter 6 Molecular Basis Of Inheritance Quiz 6Class 12 Biology Chapter 6 Molecular Basis Of Inheritance Quiz 7Class 12 Biology Chapter 6 Molecular Basis Of Inheritance Quiz 8 🏠 Back to Homepage 📘 Download PDF Books 📕 Premium PDF Books