This quiz works best with JavaScript enabled. Home > Class 12 > Class 12 Biology Chapter 6 Molecular Basis Of Inheritance – Quiz 1 🏠 Homepage 📘 Download PDF Books 📕 Premium PDF Books Class 12 Biology Chapter 6 Molecular Basis Of Inheritance Quiz 1 (25 MCQs) Quiz Instructions Select an option to see the correct answer instantly. 1. In a DNA strand the nucleotides are linked together by A) Glycosidic bonds. B) Phosphodiester bonds. C) Peptide bonds. D) Hydorgen bonds. Show Answer Correct Answer: B) Phosphodiester bonds. 2. Gene thatt are involved in turning on or off the transcription of a set of structural genes are called A) Operator gene. B) Redundant genes. C) Regulator genes. D) Polymorphic genes. Show Answer Correct Answer: A) Operator gene. 3. Which of the following help(s) to hold the DNA strands apart while they are being replicated? A) Single-strand DNA binding proteins. B) Topoisomerase. C) Primase. D) DNA ligase. Show Answer Correct Answer: A) Single-strand DNA binding proteins. 4. The Human Genome Project revealed that approximately what percentage of the human genome codes for proteins? A) 50%. B) 25%. C) Less than 2%. D) 10%. Show Answer Correct Answer: C) Less than 2%. 5. Hershey and Chase experiment used A) Virus and plants. B) Bacteriophage and bacteria. C) Fungi and algae. D) Human cells. Show Answer Correct Answer: B) Bacteriophage and bacteria. 6. 5-methyl uracil is a component of A) DNA. B) RNA. C) Amino acid. D) Both a and b. Show Answer Correct Answer: A) DNA. 7. A human gene is cloned in E. coli and then allowed to undergo gene expression. Upon performing downstreaming processes and testing for functionality of that gene product, it was found to be inactive. Which of the following can be a promisable reason for same? A) Coupled Transcription and Translation. B) Single type of RNA polymerase. C) Lack of Post-trancriptional machinery. D) Presence of extrachromosomal DNA along with genomic DNA. Show Answer Correct Answer: C) Lack of Post-trancriptional machinery. 8. The replication begins at a specific region called A) Replication initiation. B) Replication termination. C) Origin of replication. D) Site of binding. Show Answer Correct Answer: C) Origin of replication. 9. The process of creating mRNA based on a DNA sequence is called A) Transcription. B) Translation. C) Replication. D) Reverse transcription. Show Answer Correct Answer: A) Transcription. 10. What is the work of the sigma factor in transcription? A) Transcription initiation. B) Helicase action. C) Transcription elongation. D) Transcription termination. Show Answer Correct Answer: A) Transcription initiation. 11. Avery and his colleagues' 1944 experiment showed that DNA ..... A) Contains adenine, guanine, thymine, and cytosine. B) Consists of sugars, phosphate groups, and bases. C) Has two strands held together with hydrogen bonds. D) Was the substance that transformed the bacteria in Griffith's experiment. Show Answer Correct Answer: D) Was the substance that transformed the bacteria in Griffith's experiment. 12. The transforming principle in Griffith's experiment was later identified by Avery, MacLeod and McCarty as: A) Protein. B) RNA. C) DNA. D) Lipopolysaccharide. Show Answer Correct Answer: C) DNA. 13. The process of transofrmation is not affected by which of the following enzymes?A. DNaseB. RNaseC. PeptidaseD. Lipase A) A, B. B) A, B, C, D. C) B, C, D. D) A, B, C. Show Answer Correct Answer: C) B, C, D. 14. What does DNA have that RNA doesn't A) Presence of thymine. B) Presence of deoxyribose. C) Presence of ribose. D) Both a and b. Show Answer Correct Answer: D) Both a and b. 15. The scientists involved in the experiment that demonstrated DNA as the genetic material were: A) Watson and Crick. B) Hershey and Chase. C) All the above. D) None of the above. Show Answer Correct Answer: B) Hershey and Chase. 16. Suppose you are provided with an actively dividing culture of *E. coli* bacteria to which radioactive thymine has been added. What would happen if a cell replicates once in the presence of this radioactive base? A) DNA in both daughter cells would be radioactive. B) All four bases of the DNA would be radioactive. C) Neither of the two daughter cells would be radioactive. D) One of the daughter cells, but not the other, would have radioactive DNA. Show Answer Correct Answer: A) DNA in both daughter cells would be radioactive. 17. All of the following statements characterize DNA replication except- A) Second DNA strand is in the form of Okazaki fragments. B) DNA is synthesized in 3' to 5' direction in one strand and 5' to 3' in another. C) Follows semiconservative mode of replication. D) Overall growth of DNA chain is bi directional. Show Answer Correct Answer: B) DNA is synthesized in 3' to 5' direction in one strand and 5' to 3' in another. 18. Which of the following describes the function of the tRNA? A) TRNA has the codon required for translation. B) TRNA allows for the translocation step. C) TRNA has the RNA transcript for protein synthesis. D) TRNA brings the amino acid to the ribosome. Show Answer Correct Answer: D) TRNA brings the amino acid to the ribosome. 19. The direction of D.N.A. replication is: A) From 5' end towards 3' end. B) From 3' end towards 5' end. C) Amino terminus to carboxy terminus. D) Carboxy terminus to amino terminus. Show Answer Correct Answer: A) From 5' end towards 3' end. 20. What are those structures that appear as 'beads-on-string' in the chromosomes when viewed under electron microscope? A) Base pairs. B) Genes. C) Nucleotides. D) Nucleosomes. Show Answer Correct Answer: D) Nucleosomes. 21. The RNA involved in transporting aminoacids and reads genetic code are A) MRNA. B) RRNA. C) TRNA. D) RNAi. Show Answer Correct Answer: B) RRNA. 22. In eukaryotes, the process of processing of primary transcript involves A) Removal of introns. B) Capping at 5'end. C) Tailing (polyadenlation) at 3' end. D) All of these. Show Answer Correct Answer: B) Capping at 5'end. 23. The DNA segments in eukaryotes that do NOT code for proteins are A) Exons. B) Introns. C) Cistrons. D) Codons. Show Answer Correct Answer: B) Introns. 24. What do Bacteriophages infect A) Mice. B) Viruses. C) Humans. D) Bacteria. E) Fungus. Show Answer Correct Answer: D) Bacteria. 25. Five types of histone proteins are- A) H1, H2A, H2C, H2D & H3A. B) H1, H2A, H2B, H3 & H4. C) H1, H2A, H2, H3A & H4. D) H1, H2, H3, H4 A & H4B. Show Answer Correct Answer: B) H1, H2A, H2B, H3 & H4. 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